Final answer:
Personnel handling contaminated specimens or working with infected patients during nonsterile or sterile antineoplastic compounding need to wear PPE and follow proper hygiene practices.
Step-by-step explanation:
In the context of nonsterile or sterile antineoplastic compounding under USP 800, personnel are required to wear personal protective equipment (PPE). This includes a protective coat, face protection, and cut-resistant gloves. These measures are essential to protect against the potential hazards posed by contaminated specimens, equipment, or infected patients.
In addition to wearing PPE, personnel should also follow proper hygiene practices. Any contact with the skin should be immediately washed with detergent and warm water, followed by washing with 1 N NaOH or a 1:10 dilution of bleach for 1 minute. Contaminated waste should be incinerated or autoclaved in a strong basic solution, and instruments should be cleaned and soaked in a strong basic solution.