Final answer:
Facilities that mix high-risk level CSPs must test for microbial and endotoxin contamination to ensure safety and efficacy.
Step-by-step explanation:
The facilities that mix high-risk level CSPs must test for microbial and endotoxin contamination. This is important to ensure the safety and efficacy of the compounded sterile preparations (CSPs).
Microbial contamination refers to the presence of microorganisms such as bacteria or fungi in the CSPs, which can cause infections or other adverse reactions when administered to patients. Endotoxins, on the other hand, are toxins released by certain bacteria that can also lead to severe health complications.
To test for microbial contamination, facilities may use methods such as sterility testing and surface monitoring. Endotoxin testing can be done using methods like the Limulus amebocyte lysate (LAL) assay.