Final answer:
The minimum ISO classification for both SCAs and C-SCAs is ISO Class 7, with SCAs minimizing contamination risk in compounding processes and C-SCAs providing containment. The choice of BSC class within these areas is dictated by the BSL required for the pathogens being handled.
Step-by-step explanation:
The minimum ISO classification for segregated compounding areas (SCAs) is ISO Class 7, and for containment segregated compounding areas (C-SCAs) the minimum classification is also ISO Class 7. SCAs are designed to minimize the risk of contamination in the compounding process. Biological Safety Cabinets (BSCs) play a critical role in maintaining the required ISO standards by providing varying levels of protection. Class I BSCs are typically used for low to moderate risk exposure environments, Class II for higher levels of protection for both the personnel and the product, and Class III BSCs are used for the highest risk environments, such as BSL-4 laboratories.
BSL, or BioSafety Levels, are categorized based on the danger posed by the pathogens being handled, and dictate the containment practices needed within the laboratory. Factors like the infectiousness, severity of disease, and nature of the work being conducted are used to determine the appropriate BSL and related BSC class. Adequate training in compliance with CDC Biosafety in Microbiological and Biomedical Laboratories is essential to ensure the safety of personnel and prevent contamination.