Final answer:
In Florida, a major exception to requiring ID from a patient picking up a controlled prescription is for medical marijuana use by individuals with debilitating diseases as determined by a licensed Florida physician.
Step-by-step explanation:
The major exception to requiring ID from a patient picking up a controlled prescription under Florida law is the medical use of marijuana for individuals with debilitating diseases as determined by a licensed Florida physician. The Department of Health registers and regulates centers that produce and distribute marijuana for medical purposes and issues identification cards to patients and caregivers. This exception applies only to Florida law and does not authorize non-medical use, possession, or production of marijuana.