Final answer:
To avoid the most severe side effects of quinolones, it is important to follow the prescribed dosage and duration, avoid use in individuals with a history of tendon disorders or those taking corticosteroids, and stay hydrated to minimize the risk of phototoxicity.
Step-by-step explanation:
In order to avoid or prevent the most severe side effects of quinolones, it is important to follow the prescribed dosage and duration of the medication. Quinolones should not be used in individuals who have a history of tendon disorders or those who are taking corticosteroids, as they can increase the risk of tendon rupture. Additionally, it is advisable to stay hydrated while taking quinolones to minimize the risk of developing phototoxicity.