Question

When explaining how verapamil (Calan) produces its effects on the cardiovascular system, which of the following would the nurse integrate into the explanation? Select all that apply.

A) Reduction in the release of renin
B) Dilation of coronary arteries
C) Dilation of peripheral arteries
D) Slowed conduction through the SA and AV nodes
E) Membrane-stabilizing effects

Answer 1

Verapamil (Calan) produces its effects on the cardiovascular system by dilating coronary and peripheral arteries, as well as slowing conduction through the SA and AV nodes. Options B, C and D are correct.

Step-by-step explanation:

When explaining how verapamil (Calan) produces its effects on the cardiovascular system, the nurse would integrate the following information:

• Dilation of coronary arteries: Verapamil is a calcium channel blocker that inhibits the entry of calcium into the smooth muscle cells of the coronary arteries, leading to their dilation. This promotes increased blood flow to the heart.
• Dilation of peripheral arteries: Verapamil also causes relaxation or dilation of the smooth muscles in peripheral arteries, reducing peripheral vascular resistance and leading to a decrease in blood pressure.
• Slowed conduction through the SA and AV nodes: Verapamil inhibits the movement of calcium ions into the cells of the SA and AV nodes, which slows down the conduction of electrical impulses through these nodes. This results in a decrease in heart rate and a reduction in the force of cardiac contraction.