Final answer:
Administration of vasodilators would be the most likely therapeutic measure to decrease afterload in this patient with right- and left-sided heart failure.
Step-by-step explanation:
Increased afterload is the tension that the ventricles must develop to pump blood effectively against the resistance in the vascular system. In this patient, the increased blood pressure indicates increased afterload. To decrease afterload, administration of vasodilators would be the most appropriate therapeutic measure. Vasodilators relax the smooth muscles in the blood vessels, reducing the resistance and decreasing afterload. This helps the heart pump blood more easily and improves cardiac function.