Final answer:
The nurse should promptly administer oxygen and prepare for an epinephrine injection, as the patient is showing signs of respiratory distress due to an allergic reaction from a bee sting.
Step-by-step explanation:
The practical nurse should recognize that a respiratory rate of 28 and an oxygen saturation level of 80% on room air are indications of respiratory distress, likely due to an allergic reaction from the bee sting. Immediate interventions should include administering oxygen to improve oxygen saturation and potentially preparing for an epinephrine injection to reduce the allergic reaction and prevent further airway compromise. It is essential that the nurse acts quickly to address both the respiratory rate and low oxygen saturation to prevent the situation from deteriorating, as severe allergic reactions can lead to anaphylaxis, a life-threatening condition that requires immediate medical attention.