Final answer:
Applied consent is inappropriately given when individuals cannot make an informed decision, are coerced, or do not have full comprehension of the research due to inadequate information.
Step-by-step explanation:
Applied consent would not be legally appropriate when an individual is not capable of giving informed consent, is coerced, or is provided with misleading or incomplete information about the research they are participating in. This is critical to protect individuals from exploitation, especially those from vulnerable populations. For instance, if individuals are coerced into participating in a study by being offered benefits such as good behavior credit or if they are not fully informed of the nature of the study, including whether they may receive a placebo instead of the actual medication being tested, their consent is not ethically sound. In any research involving human subjects, it is imperative to provide clear, complete, and comprehensible information so that participants can give truly informed consent without any form of coercion, thus respecting their autonomy and rights.