Question

True statements about the function of excipients used in tablet formulations include

I.binders promote granulation during the wet granulation process.
II.glidants help promote the flow of the tablet granulation during manufacture.
III.lubricants help the patient swallow the tablets.

A. I only is correct
B. III only is correct
C. I and II are correct
D. II and III are correct
E. I, II, and III are correct

Answer 1

The correct answer is C. I and II are correct, because binders promote granulation and glidants improve granulation material flow during tablet manufacturing, whereas lubricants primarily prevent sticking to manufacturing equipment.

Step-by-step explanation:

The question pertains to the function of excipients in tablet formulations. Excipients have several functions, including:

• Binders promote the granulation process to ensure that granules are formed properly during the wet granulation process.
• Glidants improve the flow of the granulation material during the tablet manufacturing process.

However, lubricants are designed to prevent sticking to the equipment during the tablet manufacturing process and do not aid in swallowing the tablet. That is more related to the tablet's shape, coatings, or size. Hence, the correct answer to the question is that statements I and II are true, so C. I and II are correct.