Final answer:
Prevnar 13 should not be given to someone with a severe allergic reaction to any component of Prevnar 13 or any toxoid-containing vaccines. Toxoid vaccines contain inactivated toxins that can stimulate an immune response.
Step-by-step explanation:
Prevnar 13 should not be given to anyone with a history of severe allergic reaction to any component of Prevnae 13 or any toxoid-containing vaccines.
Toxoid vaccines, like subunit vaccines, do not introduce a whole pathogen to the patient. They contain inactivated toxins that have been treated to remove their toxicity but retain their ability to stimulate an immune response.