Final answer:
ACE inhibitors and angiotensin receptor blockers (ARBs) are recommended to manage hypertension and protect kidney function in nonpregnant women with type 2 diabetes, often used when GFR is reduced but not severely impaired.
Step-by-step explanation:
The management of hypertension in patients with type 2 diabetes is critical due to the increased risk of cardiovascular diseases in these individuals. A key component in this therapeutic strategy is the use of medications like ACE inhibitors or angiotensin receptor blockers (ARBs). These medications act by inhibiting the effects of angiotensin II, a potent vasoconstrictor that would otherwise increase systemic blood pressure and reduce glomerular filtration rate (GFR). When GFR is estimated, it is a measurement of how well the kidneys are cleaning the blood. ACE inhibitors and ARBs are recommended in nonpregnant women with type 2 diabetes and hypertension to protect kidney function and control blood pressure.
While the question does not specify an exact GFR value, it is understood that these medications are typically indicated when GFR is reduced but not severely impaired. They are beneficial in slowing the progression of kidney disease by reducing hypertension's damaging effects on the renal blood vessels, thereby preserving GFR. In clinical practice, GFR thresholds and individual patient factors determine the initiation of these therapies.