Final answer:
The Clinical Pharmacology section of a package insert lists recommended doses, dosing schedules, and administration requirements. When determining the dosage of a drug, factors such as age, weight, liver or kidney dysfunction, pharmacokinetics, drug class, and patient responsiveness need to be considered. Common side effects of drugs include nausea, headache, dizziness, and drowsiness, and these can be influenced by factors like drug interactions, allergies, and individual patient characteristics.
Step-by-step explanation:
The Clinical Pharmacology section of a package insert lists recommended doses, dosing schedules, and administration requirements.
When determining the dosage of a drug, there are several factors to consider:
- Age and weight: In children, the dose is based on their mass, while adults and children 12 years and older typically have a standard dose regardless of their mass.
- Liver or kidney dysfunction: Patients with a history of liver or kidney dysfunction may experience reduced drug metabolism or clearance, leading to increased drug levels and a higher risk of side effects.
- Pharmacokinetics: The way drugs are absorbed, metabolized, and eliminated from the body can affect their dosing.
- Drug class: Each drug class is associated with different potential side effects that should be considered when determining the dosage.
- Patient responsiveness: Some patients may require higher or lower doses of a drug based on their individual response to treatment.
Common side effects associated with drugs include nausea, headache, dizziness, and drowsiness. Factors that can contribute to these side effects include interactions with other drugs, drug allergies, and individual patient characteristics.