Final answer:
NCD with Lewy bodies is characterized by the presence of Lewy bodies in dopaminergic neurons in the brain, while NCD due to Parkinson's disease is mainly caused by the loss of dopaminergic neurons in the substantia nigra.
Step-by-step explanation:
The difference between NCD with Lewy bodies and NCD due to Parkinson's disease is that while both types are neurodegenerative diseases, NCD with Lewy bodies is characterized by the presence of Lewy bodies in dopaminergic neurons in the brain. Lewy bodies are abnormal protein clumps that are often seen in Parkinson's disease as well. However, in NCD with Lewy bodies, the prevalence of Lewy bodies is often associated with the severity of the disease. In contrast, NCD due to Parkinson's disease is mainly caused by the loss of dopaminergic neurons in the substantia nigra, resulting in motor symptoms such as tremor, slowed movement, and rigidity.