Final answer:
Tricyclic antidepressants can increase the concentrations of certain medications in the body.
Step-by-step explanation:
Tricyclic antidepressants (TCAs) are a class of drugs used for the treatment of major depression. Examples include imipramine and amitriptyline. TCAs have the potential to interact with other medications and increase their concentrations in the body. One example is the interaction between TCAs and selective serotonin reuptake inhibitors (SSRIs), which can increase the concentration of TCAs and potentially lead to adverse effects.