Final answer:
A hypothesis is a tentative explanation, while a theory is a well-substantiated explanation. The main difference between a hypothesis and a theory is that a hypothesis is a testable prediction that can be further investigated, whereas a theory is a well-supported and widely accepted explanation that has been repeatedly tested and supported by experimental evidence.
Step-by-step explanation:
A hypothesis is a tentative explanation, while a theory is a well-substantiated explanation. A hypothesis is an educated guess about a natural phenomenon, while a scientific theory is an explanation of the natural world with experimental support. The main difference between a hypothesis and a theory is that a hypothesis is a testable prediction that can be further investigated, whereas a theory is a well-supported and widely accepted explanation that has been repeatedly tested and supported by experimental evidence.