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Is it important that blood types are matched for safe transfusion?

User Lexpj
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Final answer:

It is essential to match blood types for transfusions to prevent adverse immune reactions like hemolytic transfusion reactions (HTR). In emergencies, type O may be used, but Rh factors must also be considered to avoid complications. Ideally, donor and recipient blood types, including ABO and Rh, should be fully compatible.

Step-by-step explanation:

Matching blood types for a transfusion is critical to ensure the safety and success of the procedure. Blood types must be compatible because different blood groups have unique antibodies that will attack foreign antigens.

For instance, a type B recipient should ideally only receive blood from a type B donor to avoid the risk of a hemolytic transfusion reaction (HTR), a potentially lethal event where the recipient's immune system attacks the transfused blood cells.

In emergencies where there's a threat to life due to acute hemorrhage, and there's no time to cross match blood types, type O blood from a universal donor may be used. However, if the type O donor has been previously exposed to the Rh antigen and the recipient is Rh negative, this can lead to complications like agglutination. The ideal scenario is always to match the donor's and recipient's blood, including both the ABO and Rh identifications, to prevent a transfusion reaction. While emergency protocols can bend these rules slightly, the safest approach lies in complete compatibility.

User Neerajkh
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