Final answer:
The Amazon EC2 instance deployment option that allows a workload to run on a specific physical server is using a Dedicated Host. This is suitable when software licensing dictates that the server hardware must be exclusively used by a single customer.
Step-by-step explanation:
To meet software licensing requirements that specify the workload must run on a specific, physical server, the appropriate Amazon EC2 instance deployment option is Dedicated Hosts. A Dedicated Host is a physical server with EC2 instance capacity fully dedicated to a single customer's use. This option allows companies to use their existing server-bound software licenses and ensures that the server's hardware is not shared with other customers. It is the optimal choice for meeting compliance and regulatory requirements that mandate the exclusive use of a physical server.