Final answer:
The pseudo-Pelger-Huet anomaly is related to changes in the morphology of neutrophils, leading to hypo-segmentation of their nuclei.
Step-by-step explanation:
The pseudo-Pelger-Huet anomaly is associated with abnormalities in neutrophils. Specifically, it refers to a morphological change in the neutrophils where they exhibit hypo-segmentation, making them appear with a single-lobed nucleus instead of the usual multi-lobed structure. Pseudo-Pelger-Huet anomaly can occur as an inherited benign condition or may be acquired, often seen in myelodysplastic syndromes or other myeloproliferative disorders.