Question

Of the following, the disease most closely associated with pale blue inclusions in granulocytes and giant platelets is?

1) Sickle cell anemia
2) Gaucher disease
3) Tay-Sachs disease
4) Chediak-Higashi syndrome

Answer 1

Chediak-Higashi syndrome is the disease most closely associated with pale blue inclusions in granulocytes and giant platelets. It is a rare autosomal recessive disorder that affects lysosomes and leads to abnormal lysosomal function.

Step-by-step explanation:

The disease most closely associated with pale blue inclusions in granulocytes and giant platelets is Chediak-Higashi syndrome.

Chediak-Higashi syndrome is a rare autosomal recessive disorder that affects lysosomes, which are responsible for breaking down cellular waste. The inclusions in granulocytes and giant platelets seen in Chediak-Higashi syndrome are a result of abnormal lysosomal function.