Question

Which of the following is the theoretical proposition that the lifespan of any species is subject to a genetically preprogrammed limit to the number of times cells have the capability to replicate themselves?

1) Genetic Limitation Theory
2) Cellular Replication Theory
3) Lifespan Preprogramming Theory
4) Hayflick Limit Theory

Answer 1

The theoretical proposition that the lifespan of any species is subject to a genetically preprogrammed limit to the number of times cells have the capability to replicate themselves is known as the Hayflick Limit Theory. This theory states that cells can only divide a limited number of times before they reach a state of replicative senescence, where they become unable to divide further.

Step-by-step explanation:

The theoretical proposition that the lifespan of any species is subject to a genetically preprogrammed limit to the number of times cells have the capability to replicate themselves is known as the Hayflick Limit Theory.

The Hayflick Limit Theory states that cells can only divide a limited number of times before they reach a state of replicative senescence, where they become unable to divide further. This limit is believed to be determined by the shortening of telomeres, which are protective caps on the ends of chromosomes, during each cell division.

Once the telomeres become too short, cells enter a state of permanent growth arrest called cellular senescence. This theory was proposed by Leonard Hayflick in the 1960s, based on his observations of human cells in culture.