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What is the only antigen mismatch that O blood type can have?

1) A
2) B
3) AB
4) O

User Gcerar
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1 Answer

4 votes

Final answer:

O blood type can have an antigen mismatch with A, B, or AB antigens due to the presence of anti-A and anti-B antibodies in type O blood.

Step-by-step explanation:

The only antigen mismatch that O blood type can have is with either A, B, or AB antigens because type O blood lacks any A or B antigens. People with type O blood have both anti-A and anti-B antibodies, which would react with any A or B antigens introduced into the body through a transfusion. Therefore, while individuals with type O blood can donate to any ABO blood type due to the absence of antigens that could cause an immune reaction, they can only receive type O blood to avoid an antigen-antibody reaction that could lead to hemolysis.

User Jim Parker
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