Final answer:
Mantle Cell Lymphoma involves the Cyclin D1 gene, which is critical for cell cycle regulation, particularly in the transition from the G1 phase to the S phase.
Step-by-step explanation:
The lymphoma that involves the Cyclin D1 gene is known as Mantle Cell Lymphoma (MCL). The Cyclin D1 gene is crucial for regulating the cell cycle; it encodes for a protein that helps control the transition from the G1 phase to the S phase of the cell cycle. MCL is a type of non-Hodgkin lymphoma (NHL) that typically affects a subtype of B lymphocytes found in the outer edge of a lymph node or mantle zone. The aberrant overexpression of the Cyclin D1 protein due to a genetic alteration can drive cells to proliferate excessively, eventually leading to this form of cancer. Therefore, identifying the involvement of Cyclin D1 can be critical for diagnosing MCL and choosing the proper course of treatment.