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When looking at myelinated neurons, what is the propagation of the signal?

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Final answer:

In myelinated neurons, saltatory conduction allows action potentials to travel faster by 'jumping' from one node of Ranvier to the next, as opposed to the continuous propagation in unmyelinated neurons which is slower. Myelination provides insulation and increases the conduction speed, while nodes of Ranvier help conserve energy.

Step-by-step explanation:

Propagation of a Signal in Myelinated Neurons

The propagation of an action potential in myelinated neurons differs significantly from that in unmyelinated neurons. In myelinated axons, the action potential travels quickly because the myelin sheath acts as an insulator, preventing voltage loss and allowing the signal to move rapidly in a process known as saltatory conduction. This results in the signal 'jumping' from one node of Ranvier to the next, where voltage-gated Na+ channels regenerate the depolarization necessary for the action potential to continue. The myelination ensures both greater speed and insulation from signals in other nerves, which limits cross talk. In contrast, action potentials in unmyelinated axons require continuous regeneration along the entire length of the axon, which is slower and more energy-intensive.

Furthermore, myelinated axons offer enhanced conductivity due to their increased diameter, reducing resistance for ion diffusion. Demyelinating diseases, like multiple sclerosis, can lead to a slowdown in action potential conduction due to the loss of insulating properties of the myelin sheath. The nodes of Ranvier also play a crucial role in conserving energy within the neuron since ion channels are concentrated in these areas rather than distributed along the entire length of the axon.

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