Final answer:
The IRB consideration for review of phase I research is informed consent.
Step-by-step explanation:
The IRB consideration for review of phase I research is informed consent. Informed consent is a process where research participants are provided with information about the study, including any potential risks and benefits, before deciding to participate. It ensures that participants are fully informed and able to make a voluntary decision to participate. The informed consent form must be signed by participants or their legal guardians.