Final answer:
The subject enrollment log as per Good Clinical Practice should be maintained by the investigator, ensuring adherence to ethical requirements and protection of participant information.
Step-by-step explanation:
According to Good Clinical Practice (GCP), the subject enrollment log should be kept in the possession of the investigator. This log is a part of the essential documents relating to the clinical trial that the investigator is responsible for maintaining. GCP guidelines mandate meticulous record-keeping to ensure the protection of human research participants, which includes preserving the confidentiality of the subjects' records, adhering to the ethical requirement of informed consent, and safeguarding the rights and safety of participants. The enrollment log helps track the participants who have consented to be part of the study and must be securely maintained under the investigator's care. While other parties such as the sponsor, ethics committee, and regulatory authority may have access to certain study documents for monitoring, audits, or inspections, the responsibility for maintaining the log rests with the investigator.