Final answer:
Immunoglobulin E (IgE) is associated with allergic reactions characterized by histamine release and an increase in eosinophils, leading to symptoms ranging from mild to severe, such as anaphylactic shock.
Step-by-step explanation:
The type of immunoglobulin reaction associated with histamine release and an increased number of eosinophils in tissue, or noticed in your complete blood count, is associated with Immunoglobulin E (IgE). IgE is known for its role in allergic responses and is involved in Type I hypersensitivity reactions. When an individual sensitized to an allergen is exposed to it again, IgE antibodies on the surface of mast cells bind to the allergen. This binding stimulates mast cells to release various inflammatory molecules, including histamine, which leads to allergy symptoms like vasodilation, edema, rash, and an increased number of eosinophils in tissues and blood.
Examples of allergic responses include mild symptoms such as sneezing and itchy, watery eyes, and more severe reactions like anaphylactic shock, which can be life-threatening.