Question

What are combo products specifically marketed for in order to reduce the risk of NSAID induced ulcers?

1) Reducing pain and inflammation
2) Preventing stomach ulcers
3) Boosting the immune system
4) Improving digestion

Answer 1

Combo products containing NSAIDs are marketed for preventing stomach ulcers by including protective agents that help maintain the stomach lining while still offering pain and inflammation reduction benefits.

Step-by-step explanation:

Combo products that include nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen are specifically marketed for preventing stomach ulcers. These medications are effective in reducing pain and inflammation, but long-term use can increase the risk of gastrointestinal ulcers and bleeds. To mitigate this risk, combo products may include components like proton pump inhibitors or other medications that help protect the stomach lining.

NSAIDs work by blocking the enzymes responsible for prostaglandin synthesis, which is necessary for the inflammatory response, but unfortunately, they also reduce the protective prostaglandins in the stomach lining, leading to ulcers. The addition of protective agents helps prevent ulcer formation while still providing the therapeutic effects of the NSAID. It's important to note that for ulcers caused by H. pylori infection, antibiotics are effective, and switching to other classes of pain relievers can allow healing of ulcers caused by NSAID use.

Answer 2

Combo products with NSAIDs are marketed for preventing stomach ulcers by combining NSAIDs with protective medications to reduce ulcer risk associated with NSAID use (option 2).

Step-by-step explanation:

Combo products containing nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and the prescription drug Celebrex (celecoxib) are specifically marketed for preventing stomach ulcers (2). NSAIDs can reduce pain and inflammation, but can also lead to an increased risk of gastrointestinal ulcers and bleeds due to their action on prostaglandin synthesis. By combining NSAIDs with medications that protect the stomach lining or reduce stomach acid, these products aim to minimize the risk of ulcers, which are not mainly due to diet but are a complication that can arise from regular NSAID use.