Question

When choosing the clarithromycin triple treatment regimen, if a patient has a penicillin allergy, what can you do?

1) Switch to an alternative antibiotic
2) Continue with the clarithromycin triple treatment regimen
3) Consult an allergist for desensitization therapy
4) Discontinue the treatment

Answer 1

If a patient has a penicillin allergy, the clarithromycin triple treatment regimen should be modified by switching amoxicillin with an alternative antibiotic that the patient is not allergic to, such as a bismuth subsalicylate-based regimen.

Step-by-step explanation:

When selecting a clarithromycin triple treatment regimen for a patient with a penicillin allergy, the appropriate course of action would be to switch to an alternative antibiotic. Clarithromycin triple therapy typically includes lansoprazole, amoxicillin, and clarithromycin.

Since amoxicillin is a penicillin derivative, using it could result in a severe allergic reaction. Patients allergic to penicillin could be treated with a bismuth subsalicylate-based regimen (such as bismuth, metronidazole, and tetracycline) or another appropriate substitute guided by the healthcare provider's discretion and antibiotic sensitivity patterns.