Question

An miRNA has the sequence 5′-GAUCGCAUUCAG 3′. Which of the following motifs on mRNA would most likely be a target of this miRNA?

Answer 1

The target motif on mRNA for the given miRNA sequence would be 3′-CUAGGCGUUAUC 5′.

Step-by-step explanation:

The miRNA sequence 5′-GAUCGCAUUCAG 3′ is complementary to the mRNA sequence 3′-CUAGGCGUUAUC 5′. To find the target motif on mRNA, we need to identify the region on mRNA where the miRNA binds with complementary base pairing. In this case, the complementary region on mRNA would be 3′-CUAGGCGUUAUC 5′, which is the reverse complement of the miRNA sequence. Therefore, the target motif on mRNA would be 3′-CUAGGCGUUAUC 5′.