Question

Do the lymphoblasts in T-ALL express CD10?
1) Yes
2) No
3) Cannot be determined

Answer 1

Generally, lymphoblasts in T-ALL do not express CD10, as this marker is more closely associated with B-cell acute lymphoblastic leukemia rather than T-cell lineage.

Step-by-step explanation:

The question concerns the expression of CD10 on lymphoblasts in T-cell acute lymphoblastic leukemia (T-ALL). CD10 is a cell surface marker commonly associated with acute lymphoblastic leukemias, but its expression may vary depending on the lineage of the leukemia. In the case of T-ALL, lymphoblasts typically do not express CD10 as it is more commonly associated with B-cell acute lymphoblastic leukemia (B-ALL). Instead, T-ALL is characterized by the presence of other T-cell antigens. Therefore, the answer to whether the lymphoblasts in T-ALL express CD10 is generally no.