Question

Acute lymphoblastic leukemia is associated with Down syndrome and usually arises after the age of 5 years. What is the association between acute lymphoblastic leukemia and Down syndrome?

1) There is no association between acute lymphoblastic leukemia and Down syndrome
2) Acute lymphoblastic leukemia is more common in individuals with Down syndrome
3) Acute lymphoblastic leukemia is less common in individuals with Down syndrome
4) The association between acute lymphoblastic leukemia and Down syndrome is unclear

Answer 1

Down syndrome is associated with a higher risk of developing acute lymphoblastic leukemia (ALL).

Step-by-step explanation:

Individuals with Down syndrome are more likely to develop acute lymphoblastic leukemia (ALL) compared to individuals without Down syndrome. This is because of the increased risk of chromosomal abnormalities, including trisomy 21, which is the underlying genetic cause of Down syndrome. Acute lymphoblastic leukemia is a type of cancer where there is an overproduction of young, immature leukocytes. The cells do not function properly, leading to health issues.