Final answer:
Lymphopenia may occur due to autoimmune destruction in diseases like SLE.
Step-by-step explanation:
Lymphopenia may occur due to autoimmune destruction in diseases like Systemic Lupus Erythematosus (SLE). This is true. In SLE, autoantibodies produced by the immune system attack and destroy lymphocytes, leading to a decrease in their count in the blood. Lymphopenia can also be caused by other factors like viral infections, certain cancers, chronic illnesses, immunosuppression, and drug therapies involving steroids.