Question

Acute lymphoblastic leukemia is subclassified into B-ALL and T-ALL based on surface markers. What are the surface markers used for subclassification?

1) CD19 and CD10
2) CD3 and CD5
3) CD20 and CD22
4) CD34 and CD117

Answer 1

Acute lymphoblastic leukemia is subclassified into B-ALL and T-ALL based on specific surface markers. B-ALL is characterized by the expression of CD19 and CD10, while T-ALL is characterized by the expression of CD3 and CD5.

Step-by-step explanation:

Acute lymphoblastic leukemia (ALL) is subclassified into B-cell ALL (B-ALL) and T-cell ALL (T-ALL) based on surface markers, specifically cluster of differentiation (CD) molecules.

B-ALL is characterized by the expression of CD19 and CD10 on the surface of the cancerous cells, while T-ALL is characterized by the expression of CD3 and CD5.