Question

Holoprosencephaly may be related to mutations in the sonic hedgehog signaling pathway. This is an example of a developmental field defect which is when an initial embryonic disturbance leads to multiple malformations by disrupting the development of adjacent tissues and structures within a particular region. What is the name of this type of defect?

1) Holoprosencephaly
2) Sonic hedgehog signaling pathway
3) Developmental field defect
4) Embryonic disturbance

Answer 1

A developmental field defect is the name of this type of defect, which occurs when an initial embryonic disturbance disrupts the development of adjacent tissues and structures in a specific region. In the case of holoprosencephaly, mutations in the sonic hedgehog signaling pathway can lead to multiple malformations.

Step-by-step explanation:

The name of the type of defect described in the question is Developmental field defect. It occurs when an initial embryonic disturbance disrupts the development of adjacent tissues and structures within a particular region, leading to multiple malformations. In the case of holoprosencephaly, mutations in the sonic hedgehog signaling pathway can cause disruptions in the development of the brain and facial structures, resulting in a wide range of malformations.