Question

What is the mode of inheritance of Friedreich ataxia?

1) Autosomal dominant
2) Autosomal recessive
3) X-linked dominant
4) X-linked recessive

Answer 1

The mode of inheritance of Friedreich ataxia is autosomal recessive, meaning that an individual must inherit two copies of the faulty gene to have the disorder. Other examples of genetic disorders inherited in an autosomal recessive pattern include cystic fibrosis, sickle cell anemia, and Tay-Sachs disease.

Step-by-step explanation:

The mode of inheritance of Friedreich ataxia is autosomal recessive. This means that for an individual to have Friedreich ataxia, they must inherit two copies of the faulty gene, one from each parent.

With autosomal recessive inheritance, both males and females have an equal chance of being affected by the disorder. In this pattern of inheritance, individuals who are carriers (heterozygous) for the disorder do not display symptoms but can pass on the faulty gene to their offspring.

Other examples of genetic disorders inherited in an autosomal recessive pattern include cystic fibrosis, sickle cell anemia, and Tay-Sachs disease.