Final answer:
The chronic use of NSAIDs is a potential causative factor for peptic ulcer disease, while dietary factors such as spicy foods do not significantly contribute to its development. Endoscopy is often used for a definitive diagnosis of peptic ulcers.
Step-by-step explanation:
In the case of peptic ulcer disease, a potential causative factor that a nurse will identify is the chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen. This is because NSAIDs can interfere with the stomach's mucosal barrier, leading to the breakdown of this protective layer and resulting in ulcers. Other factors that can contribute to the development of peptic ulcers include infection with Helicobacter pylori. Contrary to what was once believed, dietary factors such as a high intake of spicy foods, as well as coffee and alcohol consumption, do not play a significant role in the causation of peptic ulcers.
It is also notable that peptic ulcers are not primarily due to diet, and conditions like diverticulitis can be triggered by factors other than NSAIDs. For a definitive diagnosis of peptic ulcers, an endoscopy may be required, which allows direct visualization of the stomach and duodenum.