Final answer:
Osteoporosis involves decreased bone density and weakened bone structure, occurring when bone resorption outpaces bone formation, leading to fragile bones and increased fracture risk.
Step-by-step explanation:
The pathology of osteoporosis is accurately described by the statement that it involves decreased bone density and a weakened bone structure (Option D). Osteoporosis is a condition resulting from an imbalance in bone remodeling, where the rate of bone resorption by osteoclasts exceeds the rate of bone formation by osteoblasts.
This leads to a progressive reduction in bone tissue per unit volume, causing skeletal weakness that increases the risk of fractures. It is not caused by overproduction of bone tissue, an increase in bone density, or excessive calcium intake. As the body ages, especially after menopause, hormonal changes can further contribute to this imbalance, making osteoporosis more common in older adults.