Question

the nurse is completing a preadministration assessment on a client with tuberculosis who is to start pyrazinamide. the nurse should question giving this drug after discovering which factor in the client's medical record?

Answer 1

The nurse should be cautious of pyrazinamide use in a client with a history of liver disease due to its potential for causing hepatotoxicity.

Step-by-step explanation:

The nurse should question administering pyrazinamide if the client has a history of hepatotoxicity or liver disease. Pyrazinamide is an antibiotic used in combination with other drugs like isoniazid and rifampin for the treatment of tuberculosis (TB).

It is essential to monitor for hepatotoxicity during treatment because pyrazinamide can cause liver damage, which may be acute and severe.

A thorough preadministration assessment is crucial to ensure that the patient does not have preexisting liver conditions that could be exacerbated by the use of pyrazinamide.