Question

Which of the following synaptic modifications would likely enhance postsynaptic neuron responses to glutamate release? (Select all that apply)

A. Triggering persistent activation of kinases
B. Insertion of AMPA receptors
C. Dephosphorylation of AMPA receptors
D. Increasing conductance across AMPA receptors

Answer 1

The synaptic modifications that would enhance postsynaptic neuron responses to glutamate release are triggering activation of kinases, insertion of AMPA receptors, and increasing conductance across AMPA receptors.

Step-by-step explanation:

The synaptic modifications that would likely enhance postsynaptic neuron responses to glutamate release are:

• Triggering persistent activation of kinases: Activation of kinases leads to phosphorylation of AMPA receptors, resulting in an increased conductance across AMPA receptors.
• Insertion of AMPA receptors: More AMPA receptors are inserted into the postsynaptic membrane, making the neuron more responsive to glutamate.
• Increasing conductance across AMPA receptors: This modification allows more ions to flow through AMPA receptors, enhancing the neuron's response to glutamate release.