Question

Which of the following statements about signal transduction in virus-infected cells is incorrect?

a. activation of the pi3k-akt-mtorc1 signal relay in cells infected by different viruses can promote survival of infected cells and increase rates of metabolism or translation, but has no effect on autophagy
b. the genomes of many viruses encode gene products that stimulate endocytosis
c. virus infection typically results in activation of multiple signal transduction pathways
d. degradation of flaviviral RNA may lead to induction of apoptosis

Answer 1

The statement 'degradation of flaviviral RNA may lead to induction of apoptosis' is correct, as it reflects the cellular response to virus infection where apoptosis can be triggered to prevent virus spread. Cellular defenses include recognizing and degrading viral RNA.

Step-by-step explanation:

The statement "degradation of flaviviral RNA may lead to induction of apoptosis" is about the processes that occur in virus-infected cells. In this context, signal transduction refers to how cells respond to the presence of a virus, and one possible outcome is the induction of apoptosis, or programmed cell death. When a virus infects a cell, the cellular machinery may recognize viral components like RNA, and this can trigger defense responses.

One such response is the activation of pathways that lead to apoptosis, helping to prevent the spread of the virus. Flaviviruses, like many other viruses, can be targeted by these cellular defense mechanisms, and the degradation of their RNA could indeed trigger apoptotic pathways. Some reasons why cells might not enter apoptosis when expected include mutations that prevent initiation of apoptosis signaling, loss of expression of receptors for apoptosis-inducing ligands, or overexpression of growth factor pathways that inhibit apoptosis.