Final answer:
The nurse should prioritize assessing for hepatotoxicity, neurotoxicity, and hematologic toxicity (anemia) as these are significant side effects of isoniazid treatment for tuberculosis.
Step-by-step explanation:
The nurse overseeing the care of a client receiving first-line treatment for active tuberculosis should prioritize the assessment of hepatotoxicity, neurotoxicity, and hematologic toxicity (anemia) when monitoring for adverse effects of isoniazid treatment. Isoniazid is known to cause these side effects, which can be significant and require close monitoring. Hepatotoxicity, or liver damage, may present symptoms such as fatigue, nausea, jaundice, or elevated liver enzymes. Neurotoxicity may cause symptoms like numbness, tingling, or burning sensation in the extremities (peripheral neuropathy), which should be reported immediately. Lastly, hematologic toxicity can lead to anemia, with signs like pallor, fatigue, or shortness of breath.
The nurse should prioritize assessing for hepatotoxicity when monitoring for adverse effects of isoniazid treatment. Hepatotoxicity refers to liver damage caused by drugs, and it is a potential side effect of isoniazid use. The nurse should monitor for signs and symptoms such as jaundice (yellowing of the skin and eyes), dark urine, light-colored stools, abdominal pain, and fatigue. If any of these symptoms are present, the nurse should notify the healthcare provider immediately.