Question

Estradiol has multiple effects during the follicular phase of the ovarian cycle.

Choose two from the list below.
a. Upregulation of FSH, LH, and estradiol receptors in dominant follicle
b. Inhibition of GnRH release
c. Promotion of uterine lining growth
d. Suppression of ovulation

Answer 1

Estradiol's effects during the follicular phase include the upregulation of FSH, LH, and estradiol receptors in the dominant follicle, and the promotion of uterine lining growth, both of which are crucial for a healthy menstrual cycle and fertility. The correct answer is option c.

Step-by-step explanation:

The question asks about the effects of estradiol during the follicular phase of the ovarian cycle. Estradiol, one of the primary estrogens produced by the ovaries, plays a significant role in the female reproductive system. Two of its multiple effects during the follicular phase include:

1. Upregulation of FSH, LH, and estradiol receptors in dominant follicle: Estradiol helps increase the sensitivity of the dominant follicle to FSH and LH, hormones that are essential for follicle development.
2. Promotion of uterine lining growth: Estradiol stimulates the growth of the endometrium, which is the lining of the uterus, preparing it for potential implantation and pregnancy.

These processes are critical for maintaining a regular menstrual cycle and for the eventual possibility of ovulation and pregnancy. The correct options based on the provided list are: (a) Upregulation of FSH, LH, and estradiol receptors in dominant follicle and (c) Promotion of uterine lining growth.