Final answer:
Individuals with three gene deletion alpha-thalassemia have 1 total gene for alpha globin.
Step-by-step explanation:
α-thalassemia due to a three gene deletion presents with HbH disease and severe anemia. The three gene deletion means that three genes for the alpha chain of globin are missing. In normal individuals, there are four copies of the alpha globin gene. Therefore, the total genes for alpha globin in individuals with three gene deletion alpha-thalassemia is 1.