Question

Sideroblastic anemia is characterized by increased ferritin. What are the other characteristics of sideroblastic anemia?

1) Decreased hemoglobin
2) Increased iron in the bone marrow
3) Ringed sideroblasts in the bone marrow
4) Elevated transferrin saturation
5) All of the above

Answer 1

Sideroblastic anemia is characterized by increased ferritin and several other characteristic features, including decreased hemoglobin, increased iron in the bone marrow, ringed sideroblasts in the bone marrow, and elevated transferrin saturation.

Step-by-step explanation:

Sideroblastic anemia is characterized by increased ferritin and has several other characteristic features:

1. Decreased hemoglobin: Sideroblastic anemia leads to a decrease in the level of hemoglobin in the blood, which can result in symptoms such as fatigue, weakness, and shortness of breath.
2. Increased iron in the bone marrow: Along with increased ferritin, sideroblastic anemia also involves an accumulation of iron within the bone marrow.
3. Ringed sideroblasts in the bone marrow: Sideroblastic anemia is characterized by the presence of ringed sideroblasts, which are abnormal red blood cell precursors that contain iron granules.
4. Elevated transferrin saturation: Transferrin is a protein that transports iron in the blood. In sideroblastic anemia, transferrin saturation is often elevated, indicating increased iron levels in the body.

Therefore, the correct option is 5) All of the above.