Question

β-thalassemia mutations in β-globin genes result in absent (β0) or diminished (β+) production of the β-globin chain. What is the effect of β-thalassemia mutations on the production of the β-globin chain?

Answer 1

The function of the β-globin chain. What is the effect of β-thalassemia mutations on the production of the β-globin chain is absent or diminished production of the β-globin chain, leading to symptoms such as anemia.

Step-by-step explanation:

Beta-thalassemia mutations in the beta-globin genes result in absent (β0) or diminished (β+) production of the β-globin chain. The beta-thalassemia mutations affect the production of the β-globin chain by reducing the synthesis rate of the β-chain of globin.

This deficiency of the β-chain leads to the formation of abnormal hemoglobins and impaired transport of oxygen by hemoglobin. As a result, individuals with beta-thalassemia experience symptoms such as anemia. So therefore beta-thalassemia mutations in the beta-globin genes result in absent or diminished production of the β-globin chain, leading to symptoms such as anemia.