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Which of the following is not a function of epidermal growth factor (EGF)?

A)stimulating epidermal repair after injury
B)accelerating production of keratin
C)stimulating synthetic activity and secretion by epithelial glands
D)promoting the division of germinative cells in the stratum lucium

User Stenerson
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2 Answers

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Final answer:

The epidermal growth factor (EGF) does not promote the division of germinative cells in the stratum lucium, which is not the correct layer for cell division; instead, EGF's functions include wound healing and tissue repair in other epidermal layers.

Step-by-step explanation:

The question asks which of the following is not a function of epidermal growth factor (EGF): A) stimulating epidermal repair after injury, B) accelerating production of keratin, C) stimulating synthetic activity and secretion by epithelial glands, or D) promoting the division of germinative cells in the stratum lucium. The correct answer to this question is D) promoting the division of germinative cells in the stratum lucium. EGF is known for its role in stimulating cell growth, wound healing, and tissue repair by causing cells to grow and divide when it binds to its receptor, EGFR. However, EGF does not promote the division of germinative cells in the stratum lucidum, which is not a layer involved in cell division. Instead, the stratum basale is responsible for the regeneration of the epidermis.

User Bevoy
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3 votes

Final answer:

The function not attributed to epidermal growth factor (EGF) is promoting the division of germinative cells in the stratum lucidum, as EGF's roles include epidermal repair, keratin production, and activating epithelial glands.

The correct answer is D) promoting the division of germinative cells in the stratum lucium.

Step-by-step explanation:

Epidermal Growth Factor (EGF) primarily functions in the epidermis to stimulate various processes that contribute to skin health and repair. However, the statement "promoting the division of germinative cells in the stratum lucium" is not accurate. The stratum lucidum is a thin, translucent layer of the epidermis found between the stratum corneum and stratum granulosum. Germinative cells, also known as basal cells, are typically found in the stratum basale, not in the stratum lucidum.

The correct functions of epidermal growth factor (EGF) include:

A) Stimulating epidermal repair after injury: EGF plays a crucial role in promoting wound healing and repairing damaged skin.

B) Accelerating production of keratin: EGF contributes to the differentiation and maturation of keratinocytes, the cells that produce the protein keratin.

C) Stimulating synthetic activity and secretion by epithelial glands: EGF influences the activity of various epithelial cells, including glandular cells, by promoting their synthetic activities and secretion.

It's important to note that EGF primarily acts on cells in the stratum basale and stratum spinosum, contributing to the regeneration and maintenance of the epidermis.

User KillerX
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