Question

Dinitrophenol (DNP) is an "uncoupler." This means that it interferes with the flow of electrons during electron transfer. Fifty years ago, DNP was given as a drug to help patients lose weight. Why would taking DNP make someone lose weight?

Answer 1

Dinitrophenol (DNP) prevents the production of ATP and converts energy into heat, leading to weight loss.

Step-by-step explanation:

Dinitrophenol (DNP) is an uncoupler that makes the inner mitochondrial membrane leaky to protons. It disrupts the normal flow of electrons during electron transfer in the electron transport chain in cellular respiration. By interfering with this process, DNP prevents the production of ATP and causes the energy released from food to be converted into heat instead, resulting in weight loss.