Final answer:
Grey's Anatomy is the TV show where Doctors Shepherd, O'Malley, and Sloan have been killed off over the course of 17 seasons.
Step-by-step explanation:
The TV show in question is Grey's Anatomy. Over the course of its 17 seasons, several medical professionals including Doctors Shepherd, O'Malley, and Sloan have been killed off. Grey's Anatomy is a medical drama that follows the lives of surgeons at Grey Sloan Memorial Hospital.