Final answer:
Systemic mycoses are usually acquired from inhaling fungal spores, which then develop in the lungs and can spread to other organs. Diseases like coccidioidomycosis and histoplasmosis are common examples of such infections. The respiratory route is the primary means of acquisition, though other modes such as puncture wounds are also possible, especially for opportunistic infections like aspergillosis in immunocompromised individuals.
Step-by-step explanation:
Most systemic mycoses are acquired from inhaling spores. These infections generally occur when an individual inhales fungal spores from the environment. The spores then develop in the lungs and can spread to other organs. While there are different ways that fungal infections can enter the body, such as through puncture wounds or insect vectors, the respiratory route is the most common for systemic mycoses.
Diseases like coccidioidomycosis and histoplasmosis are examples where inhaling spores can lead to respiratory and systemic infections. Aspergillosis can also occur in this manner but can also infect the skin through a wound or affect immunocompromised patients via healthcare settings. Treatment involves antifungal medications that can have serious side effects.